GeneAbacus 32
Unlock Accelerated Gene Editing Breakthroughs By Same-Day Genotyping
Quantify gene-editing efficiency with our PCR-free genotyping reagent kit and obtain immediate actionable results.
GeneAbacus 32 is a standardized genotyping assay that enables rapid, robust, and highly specific gene editing efficiency quantification. Specifically designed for integration with standard lab equipment, GeneAbacus 32 delivers actionable data within just five hours. GeneAbacus 32 enables optimization, target funneling, and iterations with a highly efficient use of time and resources.
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High-Efficiency Focus: Optimized for selecting clones in high-editing-efficiency pools, where minimal screening is required.
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Compact Throughput: Perfect for labs working with smaller sample sizes or targeted workflows.
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Streamlined Analysis: Supports rapid validation with reduced resources and time.
The GeneAbacus 32 kit, includes all probes, reagents, consumables and cloud-based software necessary for quantifying gene editing efficiency within a day.
5 hour Turnaround time
Analyze and quantify gene editing efficiency and specificity within 5 hours. Accelerate your funneling timelines.
Single-nucleotide specificity
Achieve single-nucleotide precision and confidence without the need to optimize probes & protocol parameters
Simple Integration
Compatible with standard laboratory equipment with minimal hands-on time. Minimize disruption to established protocols.
Standard Workflow
Same workflow works for all targets. No need to invest in dedicated optimization efforts.
Highly Precise Genotyping with GeneAbacus 32
The GeneAbacus 32 workflow begins with genomic DNA extracted from cell lines or model organisms subjected to gene editing. Utilizing our innovative, PCR-free chemistry, wild-type and edited genotypes are converted into distinct and countable fluorescent signals that are detected using low magnification fluorescence microscopy. This facilitates the precise differentiation and quantification of genotypes, ensuring exceptional specificity and accuracy in gene editing validation.
Product Specifications
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32 reactions
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100 ng purified DNA input
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5 hours turnaround time
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Amplicon sequencing level accuracy
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Single-base discrimination
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+/- 10% precision
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For human, mouse and zebrafish
Resources
Info Brochure GeneAbacus 32
Customer Case Study, July 2024
Collab with SciLifeLab, April 2023