High-Fidelity Genome Editing Confirmation
LockSeq is a targeted NGS library prep platform providing the sequence-level truth required for robust genome editing characterization. Achieve unmatched target recovery and high sensitivity on panels comprising of hundreds of sites.
Standardized Genomic Safety Validation
Countagen provides LockSeq as an end-to-end service model designed to eliminate the operational and infrastructure barriers of high-plex gene-editing validation. Focus on your therapeutic discovery while we deliver the sequence-level truth.
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Enabling High-Fidelity and Massive Scalability
Sequence-Level Truth & Resolution
Detect rare variants with absolute confidence. Our ligation-locked chemistry circularizes the target molecule before amplification, preserving the original genomic signal. By achieving high sensitivity with a suppressed noise level by consensus sequencing, we provide the high-resolution evidence required across development stages
High-Integrity Target Recovery
Ensure your characterization is complete. LockSeq is engineered to minimize target dropout by breaking the complexity wall of traditional multiplex assays. By reducing potential molecular interactions, we provide uniform and consistent coverage across every targeted locus, eliminating data gaps.
Scalable Panel Flexibility
Scale and pivot your research without workflow friction. Our modular "mix-and-match" architecture allows you to add and combine target coordinates without hassle. LockSeq chemistry produces inherently neutral circular templates compatible with all sequencing platforms, integrating seamlessly into your existing NGS infrastructure.