GeneAbacus
Streamlining Gene Editing Analysis
Validate your gene edit in-house with our all-in-one reagent kit, ensuring actionable results in just 5 hours even for high GC content regions and single-base edits.
GeneAbacus: A Standard Solution For Gene Editing Validation
Streamlining Efficiency and Accuracy
Gene editing holds immense promise to advance biological research and development, but ensuring its efficacy requires precise analysis. Countagen’s GeneAbacus empowers researchers with a novel solution to simplify and accelerate this critical step. GeneAbacus, is a bundle of reagents, consumables and software for gene editing efficiency quantification. It contains everything you need to validate your gene edit.
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Rapid Results in a Day
Gain reliable insights into gene editing efficiency and specificity within a single workday. Accelerate your research timelines.
Single-Base Precision
Bypass PCR, known for potential errors and optimization challenges. Achieve single-nucleotide precision and confidence.
Simple Integration
Compatible with standard laboratory equipment with minimal hands-on time. Minimize disruption to established protocols.
Cost-Effective
Reduced time and simplified procedures compared to traditional methods. Enjoy savings in research expenses.
Beyond the Basics: Unveiling the Science Behind GeneAbacus
Padlock Probes and Rolling Circle Amplification: Streamlined Analysis Without PCR
Our novel approach — padlock probes and rolling circle amplification — offers single-nucleotide precision, removes amplification bias and accuracy for GC-rich regions.
Starting with column-extracted genomic DNA from a gene editing experiment, Countagen’s proprietary technology converts edited and wild type sequences into individual fluorescent signals. This enables the precise validation of cell pools, cell clones and model organisms.
More on how it works here.
GeneAbacus: A Versatile Tool for Gene Edit Validation
Knockout
Gene knockouts are often used for for functional analysis of genes. GeneAbacus provides researchers with reliable knockout confirmation results to move swiftly and confidently from gene edit to function analysis.
Knock-in
Validating knock-ins is crucial for precise gene function studies but often challenging due to the complexity of ensuring accurate gene integration. GeneAbacus simplifies this process, enabling researchers to verify their knock-ins within 5 hours.
Base Editing
Base editing allows for precise single-nucleotide changes, critical for gene correction and research. GeneAbacus streamlines the validation process and ensures accurate confirmation of single base edits.
Prime Editing
Prime editing offers precise, versatile gene modifications ranging from small to large edits. GeneAbacus efficiently confirms prime edits to accelerate research journeys and discoveries.
GeneAbacus Empowers Your Discoveries
Faster Analysis
Reduce analysis time from weeks to hours. Accelerate your journey towards groundbreaking discoveries.
Confident Decisions
Gain reliable insights into editing efficiency. Make informed decisions about your research path.
Simplified Workflow
Streamline your workflow with a user-friendly and precise assay. Free up valuable research time.
Product Specifications
| Supported species | Data output | Genomic DNA input | Probe set up | Sample compatibility | Microscope Objective | Protocol time |
| Human, mouse |
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Custom probes + internal control | Pool analysis or clonal selection | 20x, NA >0.5, WD ~500 nm | ~5 hours |
Ready to Experience the GeneAbacus Difference?
Let’s Build Your Future Together
Download Resources
Customer Case Study, July 2024
Collab with SciLifeLab, April 2023
Info Brochure
Scientific Poster